Table 3.
Formulation code | Encapsulation efficiency (%) | Drug loading efficiency (%) | Drug content present in 5 mg of nanoparticle (w/w) |
---|---|---|---|
A1 | 91.98 ± 0.13 | 15.09 ± 0.18 | 0.94 ± 0.015 |
A2 | 75.87 ± 0.24* | 11.59 ± 0.33* | 0.77 ± 0.027* |
A3 | 52.82 ± 0.21* | 10.77 ± 0.14* | 0.59 ± 0.07* |
A4 | 63.94 ± 0.23* | 12.8 ± 0.26* | 0.66 ± 0.025* |
Values are expressed as mean ± SD, n = 3. Encapsulation and loading efficiencies were expressed in percentage. Drug content was expressed in mg. (*) P < 0.05 as compared with respective A1 formulation.