Table 1.
Effects of Eudragit and sucrose stearate concentrations on the encapsulation efficiency (EE), drug loading (DL), production yield (PY) and effective drug loading (EDL) of different BSA microspheres formulations.
| Formulation | Sucrose stearate | Eudragit (%) | EE (%) | DL (%) | PY (%) | EDL (%) | |
|---|---|---|---|---|---|---|---|
| (%) | (g) | ||||||
| A | 1 | 0.37 | 4.5 | 76.27 | 0.62 | 79.10 | 0.73 |
| B | 1 | 0.22 | 7.5 | 66.28 | 0.60 | 72.99 | 0.66 |
| C | 1 | 0.16 | 10.5 | 79.25 | 0.58 | 71.93 | 0.63 |
| D | 4 | 1.48 | 4.5 | 99.54 | 0.76 | 65.71 | 1.28 |
| E | 4 | 0.88 | 7.5 | 95.42 | 0.34 | 74.52 | 0.84 |
| F | 4 | 0.64 | 10.5 | 99.74 | 0.61 | 71.98 | 0.80 |
| G | 7 | 2.59 | 4.5 | 101.90 | 0.45 | 62.99 | 0.99 |
| H | 7 | 1.54 | 7.5 | 100.10 | 0.56 | 62.10 | 0.97 |
| I | 7 | 1.12 | 10.5 | 99.95 | 0.73 | 64.68 | 1.12 |