Table 1.

Inter-run accuracy and precision following a 3-batch validation of JDR and gemcitabine in rat plasma (data were mean ± SD, n = 18).

Analytes	Nominal conc. (ng/ml)	Intra-day			Inter-day
		Measured concentration (ng/ml)	Precision (RSD%)	Accuracy (RE%)	Measured concentration (ng/ml)	Precision (RSD%)	Accuracy (RE%)
JDR
	15.00	15.35 ± 1.4	9.4	−1.6	15.12 ± 0.5	3.4	−3.1
	125.00	116.13 ± 3.8	3.2	−7.1	112.60 ± 4.2	3.7	−9.9
	3200.00	3573.15 ± 61.5	1.7	11.6	3083.75 ± 25.9	0.8	1.8
Gemcitabine
	12.00	11.26 ± 1.2	10.4	4.3	11.02 ± 0.3	2.3	2.0
	125.00	124.66 ± 3.9	3.1	−0.3	129.96 ± 6.9	5.3	4.0
	3200.00	2912.59 ± 148.1	5.1	−9.0	2931.04 ± 26.2	0.9	−8.4