Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Pharmacokinetic parameters of BBR pellet after multiple administration in dogs.
| Pharmacokinetic parameters | Multiple dose groups | |
|---|---|---|
| T1/2 (h) | 30.56 ± 11.82 | 20.57 ± 15.50 |
| Tmax (h) | 18.5 ± 10.45 | 4.75 ± 3.60 |
| Cmax | 1.89 ± 0.79 | 2.07 ± 0.83 |
| AUC0-t (µg/l·h) | 57.50 ± 23.45 | 72.22 ± 35.78 |
| AUC0-∞(µg/l·h) | 60.24 ± 24.58 | 75.39 ± 36.82 |
| MRT (0-t) (h) | 33.80 ± 3.16 | 31.18 ± 4.91 |
| CLz/F (l/h) | 4,541,933 ± 1,507,548 | 3,568,186 ± 1,368,923 |
| DF | 1.75 ± 0.80 | 0.91 ± 0.65 |
