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Surface chemical composition of CEL-loaded HPMCAS microparticles prepared from the different solvent systems.
| Solvent | N/F | S/F | F/C | CEL concentration (%) |
|---|---|---|---|---|
| ACE | 0.885 | 0.308 | 0.044 | 22.7 ± 0.3 |
| ACE—EtOH (85:15) | 0.862 | 0.310 | 0.050 | 25.4 ± 1.9 |
| ACE—H2O (85:15) | 0.828 | 0.310 | 0.060 | 25.3 ± 2.1 |
| EtOH—H2O (85:15) | 1.000 | 0.364 | 0.051 | 19.3 ± 1.5 |
