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Pharmacokinetic parameters of the reference or F5 tablet after oral administration in beagle dogs (n = 6, crossover study).
| Composition | Tmax (h) | Cmax (ng/ml) | AUC0–24 h (ng·h/ml) | Relative BA% (to the reference) |
|---|---|---|---|---|
| Reference | 1.7 ± 0.5 | 67.3 ± 17.9 | 1964.7 ± 546.1 | – |
| F5 | 1.2 ± 0.7 | 61.2 ± 16.9 | 1815.6 ± 532.4 | 92.4 |
| P-value | N/A | 0.5990 | 0.5593 | – |
N/A: Not assessed
