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Effect of storage on tablet prepared by melt granulation with HPC Nisso-H.
| Parameter | 25 °C/RH 60% | 30 °C/RH 65% | 40 °C/RH 75% |
|---|---|---|---|
| Drug content (%) | 98.23 ± 1.95 | 99.40 + 0.80 | 97.73 ± 1.14 |
| Moisture (%) | 0.99 ± 0.21 | 0.91 ± 0.09 | 1.28 ± 0.18 |
| Hardness(kN) | 14.63 ± 0.61 | 14.93 ± 0.64 | 15.1 ± 0.7 |
| Friability (%) | 0.23 | 0.33 | 0.21 |
