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. 2019 May 25;14(6):595–608. doi: 10.1016/j.ajps.2019.04.004

Table 2.

Examples of recent studies on A7R-modified nanoparticles.

Carrier Therapeutic agent Compound Experimental model Results Refs.
Hybrid Silica Nanoparticle Chlorin (photosensitizer) A7R-HS-NP/TPC Glioma-bearing rat model A positive magnetic resonance imaging (MRI) contrast and intratumoral retention were increased greatly. [78], [79], [80]
Superparamagnetic iron oxide-based nanoparticles Ni0.5Zn0.5Fe2O4 A7R-SPIONs/Fe HUVEC (endothelial cells) The cell viability of HUVEC was reduced. [84]
Nanoparticles Paclitaxel A7R-CGKRKR-NP/PTX U87MG glioblastoma Apoptosis induction and anti-proliferative activity were enhanced. [87]