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. 2018 Jul 27;14(3):265–274. doi: 10.1016/j.ajps.2018.05.011

Table 2.

Major pharmacokinetic parameters [19], [30], [42], [49]52].

Parameter Tmax(h) Cmax(ng/ml) AUC(024 h)(ng/h/ml) Ref.
25-OCH3-PPD 2.25 ± 2.47 7.18 ± 3.39 26.65 ± 7.11 [30]
25-OCH3-PPD-phospholipid complexes 2.10 ± 0.55 28.07 ± 19.52 97.24 ± 40.17 [30]
Quercetin (103) 0.50 ± 0.07 0.67 ± 0.08 2.04 ± 0.38 [42]
Quercetin-phospholipid complexes (103) 0.75 ± 0.10 1.58 ± 0.11 8.12 ± 0.95 [42]
Quercetin 1.21 179.21 1368.26 [19]
Quercetin-phospholipid complexes 1.02 724.89 3321.05 [19]
Kaempferol 6.32 180.23 1139.59 [19]
Kaempferol-phospholipid complexes 5.83 323.56 2228.21 [19]
Isorhamnetin 7.21 195.96 1153.66 [19]
Isorhamnetin-phospholipid complexes 4.32 672.29 2722.37 [19]
Luteolin 2.5 ± 0.75 3410 ± 910 10,420 ± 2350 [49]
luteolin–phospholipid complexes 2 ± 0.63 9770 ± 1250 55,790 ± 5760 [49]
Berberine 0.5 66.01 ± 15.03 384.45 ± 108.62 [50]
berberine-phospholipid complexes 2 219.67 ± 6.02 1169.19 ± 93.75 [50]
Oleanolic acid (OA) 0.313 ± 0.12 59.5 ± 10.64 259.6 ± 22.98 [51]
Solidified OA-phospholipid complexes 0.46 ± 0.001 78.7 ± 10.18 360.6 ± 19.13 [51]
Rosuvastatin 1.94 ± 0.89 183.95*103± 4.56*103 671.56*103± 5.64*103 [52]
Rosuvastatin–phospholipid complexes 1.41 ± 0.95 674.17*103± 1.24*103 2018.59*103± 3.79*103 [52]