Fig. 1.
Synthesis of N-Boc-protected peramivir. (i) HCl-1, 4-dioxane, ether, room temperature, overnight; (ii) triethylamine, Boc-TU, HgCl2, DMF, room temperature, 2 h; (iii) 5% NaOH, EtOH and THF, room temperature, 3 h.
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