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Mean (± SD) plasma concentration-time of peramivir and Peramivir-l-Ile (n = 5 to 6). (
,
,
): the concentration of peramivir after oral administration of Peramivir-(CH2)2-l-Val, Peramivir and Peramivir-l-Ile, respectively, (160 mg/kg calculated as peramivir); (
): the concentration of Peramivir-l-Ile after oral administration of Peramivir-l-Ile (160 mg/kg calculated as peramivir).
