Martyns‐Yellowe 1993.
Methods | Allocation: randomised, no further details. Blindness: double ‐ drugs given by a nurse not involved in trial. Duration: 24 weeks*. Setting: prison hospital. | |
Participants | Diagnosis: schizophrenia (DSM III). History: chronic, stable, drug free. N=36. Age: 21‐40 years. Sex: all male. | |
Interventions | 1. Clopenthixol decanoate: dose 40 mg/IM. N=18.
2. Flupenthixol decanoate: dose 200 mg/IM. N=18.
Dosing regime: 4 fortnightly, 3 three‐weekly, 2 monthly = 20 weeks. Additional medication: 2mg benztropine. |
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Outcomes | Discharge.
Side effects. Unable to use ‐ Global Impression (no data). Mental state (BPRS ‐ no SD, residual % of symptoms from baseline ‐ endpoint). |
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Notes | *Last measurement at 24 weeks, although last dose was at 20 weeks. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |