Barth 1981.
Methods | Double blinded: yes. | |
Participants | N=215 European men with symptomatic BPH, age > 50. Lost to follow‐up: 67 (31%). | |
Interventions | Control 1: placebo (n=46). Treatment 2: P. africanum extract (Docosanol) 100 mg daily (n=50). Control 2: Sitosterin 30 mg (n=34). Treatment 2: P. africanum extract (Docosanol) 100 mg daily (n=37). Control 3: ERU* 300 mg (n=24). Treatment 3: P. africanum extract (Docosanol) 100 mg daily (n=24). Treatment duration: 8 weeks. | |
Outcomes | Nocturia; peak urine flow; residual volume. Adverse events. | |
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment (selection bias) | Unclear risk | B ‐ Unclear |