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. 1998 Jan 26;1998(1):CD001044. doi: 10.1002/14651858.CD001044

Barth 1981.

Methods Double blinded: 
 yes.
Participants N=215 European men with symptomatic BPH, age > 50. 
 Lost to follow‐up: 67 (31%).
Interventions Control 1: placebo (n=46). 
 Treatment 2: P. africanum extract (Docosanol) 100 mg daily (n=50). 
 Control 2: Sitosterin 30 mg (n=34). 
 Treatment 2: P. africanum extract (Docosanol) 100 mg daily (n=37). 
 Control 3: ERU* 300 mg (n=24). 
 Treatment 3: P. africanum extract (Docosanol) 100 mg daily (n=24). 
 Treatment duration: 8 weeks.
Outcomes Nocturia; peak urine flow; residual volume. Adverse events.
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk B ‐ Unclear