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. 2007 Jul 18;2007(3):CD001153. doi: 10.1002/14651858.CD001153.pub2

Misra 2005.

Methods RCT 
 128 patients randomised using a random number table 
 Patient assessment and randomisation done by independent investigators 
 Randomisation stratified by haematoma size
Participants CT‐proven ICH, within 6 days of stroke onset
Interventions IV infusion of 100 ml 20% mannitol each 4 hours for 5 days vs saline
Outcomes 1‐month case fatality 
 Functional disability at 3 months
Notes No patients lost to follow up 
 The number of those who were dead or severely disabled at 3 months can be calculated from data
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Low risk A ‐ Adequate