Figure 8.

SAHA and EGCG in combination significantly increased apoptosis of breast cancer cells. (A) MCF-7 cells treated for 3-days with the indicated compounds and then stained with annexin V and propidium iodide (n=3). Flow cytometric analysis was conducted utilizing the UAB Flow Core. (B-D) As above in MDA-MB-157, MDA-MB-231, and HCC1806 cell lines (n=3). Error bars represent standard error of the mean (SEM), and ANOVA with Tukey post-hoc tests were performed on all cell lines; * p<0.05, ** p<0.01, *** p<0.001.