Liu 2000.
Methods | Allocation: randomised (block procedure, block size of 4). Blindness: double. Duration: 12 weeks (preceeded by one week washout). Consent: written. Setting: hospital and outpatient clinic. | |
Participants | Diagnosis: schizophrenia (DSM‐II‐R). N=56. Age: mean ˜ 34 years. Sex: 15M, 23F*. History: average length of illness ˜ 8 years. Exclusions: other significant physical or psychological illness, substance abuse. | |
Interventions | 1. Risperidone: dose unknown. N=28.
2. Haloperidol: dose unknown. N=28. Trihexyhenidyl, lorazepam, propanolol as required. |
|
Outcomes | Mental state: PANSS.
Adverse effects: ESRS.
Leaving the study early. Unable to use ‐ CPT: outcome not relevant. |
|
Notes | * Sex of those who completed the trial only. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |