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. 2003 Apr 22;2003(2):CD000440. doi: 10.1002/14651858.CD000440

Liu 2000.

Methods Allocation: randomised (block procedure, block size of 4). 
 Blindness: double. 
 Duration: 12 weeks (preceeded by one week washout). 
 Consent: written. 
 Setting: hospital and outpatient clinic.
Participants Diagnosis: schizophrenia (DSM‐II‐R). 
 N=56. 
 Age: mean ˜ 34 years. 
 Sex: 15M, 23F*. 
 History: average length of illness ˜ 8 years. 
 Exclusions: other significant physical or psychological illness, substance abuse.
Interventions 1. Risperidone: dose unknown. N=28. 
 2. Haloperidol: dose unknown. N=28.
Trihexyhenidyl, lorazepam, propanolol as required.
Outcomes Mental state: PANSS. 
 Adverse effects: ESRS. 
 Leaving the study early.
Unable to use ‐ 
 CPT: outcome not relevant.
Notes * Sex of those who completed the trial only.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear