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. 2003 Apr 22;2003(2):CD000440. doi: 10.1002/14651858.CD000440

Lieberman 2001.

Trial name or title Risperidone and clozapine in chronic schizophrenia.
Methods  
Participants People severely ill with treatment resistant schizophrenia.
Interventions 1. Risperidone: 6 mg/day. 
 2. Risperidone: 16 mg/day. 
 3. Haloperidol. 
 4. Clozapine.
Outcomes Global state: CGI. 
 Mental state: PANSS. 
 Behaviour: NOSIE, Overt Aggression Scale. 
 Social improvement: Quality of Life Interview. 
 Cognitive effects. 
 Adverse effects: ESRS.
Starting date  
Contact information Sites of study: 
 Bronx Psychiatric Centre (J Lieberman. 
 Rockland Psychiatric Center, Manhattan Psychiatric Center (J Volavka)
Notes Allocation: random. 
 Blindness: double. 
 Duration: 12 weeks.