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. 2003 Apr 22;2003(2):CD000440. doi: 10.1002/14651858.CD000440

Ceskova 1993.

Methods Allocation: randomised (no further description). 
 Blindness: double (administered as monotherapy in oral solution). 
 Duration: 8 weeks. 
 Consent: not stated. 
 Setting: hospital.
Participants Diagnosis: schizophrenia & schizoaffective disorder (ICD‐9). 
 N=62. 
 Sex: 45M, 17F. 
 Age: mean ˜ 36 years. 
 History: hospitalised, chronic with mean duration of illness ˜ 10 years. 
 Exclusions: not stated.
Interventions 1. Risperidone: 2‐20mg/day. N=31. 
 2. Haloperidol: 2‐20mg/day. N=31.
Antiparkinsonian medication, minor tranquillizers or promethazine, dihydroergotamine as required.
Outcomes Adverse effects: various observed effects. 
 Leaving the study early. 
 Discharge from hospital.
Unable to use ‐ 
 Global effect: Serejskij's modified scale (no SD). 
 Mental state: BPRS (no SD). 
 Side effects: DVP (no SD), use of antiparkison medication (individual group data not given).
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear