Comparison 11. Calcitriol [1,25(OH)₂D3] versus calcium.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
11.1 Persons sustaining new non‐vertebral fracture	2		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
11.1.1 Selected on the basis of previous osteoporotic fracture	2	663	Risk Ratio (M‐H, Random, 95% CI)	1.23 [0.10, 14.78]
11.2 Persons sustaining new vertebral deformity	2		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
11.2.1 Selected on the basis of previous osteoporotic fracture	2	556	Risk Ratio (M‐H, Random, 95% CI)	1.69 [0.25, 11.28]
11.3 Persons sustaining new vertebral deformity in Tilyard study	1		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
11.3.1 Year 1	1	515	Risk Ratio (M‐H, Fixed, 95% CI)	0.80 [0.40, 1.58]
11.3.2 Year 2	1	476	Risk Ratio (M‐H, Fixed, 95% CI)	0.47 [0.26, 0.87]
11.3.3 Year 3	1	432	Risk Ratio (M‐H, Fixed, 95% CI)	0.28 [0.15, 0.52]