Falch 1987.

Study characteristics
Methods	Randomised trial Evaluation at 3 years by blinded observers 76 of 86 completed
Participants	University Hospital, Norway 86 postmenopausal women aged 50 to 65 years (mean age 59.6 years) who had sustained a fracture of the distal left forearm Disease exclusions: if incident fall was from greater than standing height, previous fracture of the right forearm, endocrine disease, malabsorption, gastric surgery, nephrolithiasis, renal failure Drug exclusions: oestrogens, anticonvulsants, glucocorticoids
Interventions	1. Calcitriol 0.5 μg daily (reduced to 0.25 μg if serum calcium rose above 2.65 mmol/L) Randomised 47, completed 39 2. Vitamin D3 400 IU daily (oral) Randomised 39, completed 37 No calcium supplements or manipulation of dietary calcium involved Duration of treatment 3 years
Outcomes	Measured at 3 years 1. Number of women sustaining new vertebral fracture 2. Number of women sustaining new hip fracture 3. Number of women sustaining other new appendicular fracture 4. BMC distal radius 5. BMC proximal radius
Notes	Additional data provided by Dr Falch by letter on site of appendicular fractures
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	States "randomized"; no other information provided
Allocation concealment (selection bias)	Unclear risk	No details provided