Nuti 2006.

Methods	Randomised, double‐blind trial, duration 18 months
Participants	11 clinical centres, Italy 148 participants (all women), mean age 64 years (N = 136)
Interventions	1. Alfacalcidol D3 1 μg tablet/day plus placebo 2. 880 IU vitamin D3 plus 1000 mg calcium/day (as calcium carbonate) plus placebo
Outcomes	Persons with new vertebral fracture, gastrointestinal adverse events, renal stones
Notes	Comparisons of different vitamin D doses; to be included when protocol revised in next update