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. 2020 Feb 20;15(2):e0229160. doi: 10.1371/journal.pone.0229160

Table 3. Odds of activities of daily living disability and instrumental activities of daily living disability for participants with at least one condition in chronic disease domain after five years of follow up, stratified by age and sexa.

Males Females
Number of participants with disease domain Number of participants with ADL disability Odds (95% CI) of ADL disability for participants with at least one condition in chronic disease domainb Number of participants with disease domain Number of participants with ADL disability Odds (95% CI) of ADL disability for participants with at least one condition in chronic disease domainb
Activities of daily living disability
65–74 years
cardiometabolic 441 83 1.94 (1.38–2.73) 446 97 1.88 (1.39–2.55)
musculoskeletal 711 105 1.29 (0.91–1.84) 1055 173 1.51 (1.06–2.15)
sensory 465 74 1.36 (0.97–1.92) 490 85 1.11 (0.82–1.52)
respiratory 233 45 1.56 (1.05–2.32) 193 49 1.93 (1.32–2.82)
neurological 141 31 1.89 (1.20–2.98) 106 31 2.23 (1.39–3.57)
75+ years
cardiometabolic 522 204 1.27 (1.01–1.61) 686 322 1.27 (1.05–1.55)
musculoskeletal 832 317 1.36 (1.08–1.71) 1420 621 1.26 (1.02–1.56)
sensory 738 285 1.34 (1.06–1.68) 1059 489 1.38 (1.15–1.67)
respiratory 296 121 1.28 (0.98–1.68) 284 133 1.12 (0.86–1.46)
neurological 348 165 1.94 (1.50–2.52) 336 202 2.55 (1.99–3.28)
Instrumental activities of daily living disability
65–74 years
cardiometabolic 369 151 1.78 (1.36–2.34) 307 125 1.91 (1.45–2.53)
musculoskeletal 617 215 1.28 (0.98–1.67) 822 261 1.48 (1.12–1.95)
sensory 388 147 1.47 (1.12–1.93) 365 119 1.10 (0.83–1.45)
respiratory 184 84 1.91 (1.37–2.67) 128 57 1.90 (1.29–2.80)
neurological 114 55 2.07 (1.37–3.11) 66 31 2.05 (1.21–3.46)
75+ years
cardiometabolic 326 191 1.45 (1.10–1.91) 316 184 1.22 (0.93–1.60)
musculoskeletal 555 304 1.16 (0.89–1.51) 790 442 1.33 (1.02–1.72)
sensory 475 272 1.41 (1.09–1.84) 559 322 1.32 (1.04–1.68)
respiratory 170 104 1.49 (1.06–2.11) 127 77 1.27 (0.86–1.87)
neurological 196 132 2.16 (1.54–3.04) 144 103 2.39 (1.61–3.55)

a All analyses adjusted for sex, level of education, marital status and living situation. Models also adjusted for other disease domains.

b Disease clusters: OR for having versus not having at least 1 condition in the cluster