Table 5. Population attributable risk for instrumental activities of daily living disability by disease cluster after five years of follow up, stratified by age and sexab.
| Age 65–74 | Age 75+ | |||||||
|---|---|---|---|---|---|---|---|---|
| Males | Females | Males | Females | |||||
| PAR | 95% CI | PAR | 95% CI | PAR | 95% CI | PAR | 95% CI | |
| 1 domain | ||||||||
| cardiometabolic | 12.7 | (6.4–18.9) | 12.0 | (6.5–17.5) | 5.6 | (1.4–9.8) | ||
| musculoskeletal | 17.2 | (5.3–29.2) | 8.8 | (0.8–16.8) | ||||
| sensory | 8.7 | (2.5–15.0) | 7.7 | (1.9–13.4) | 6.2 | (0.9–11.4) | ||
| respiratory | 7.3 | (3.3–11.3) | 5.1 | (1.8–8.4) | 3.1 | (0.4–5.8) | ||
| neurological | 5.0 | (2.0–8.0) | 3.0 | (0.6–5.4) | 6.9 | (3.9–10.0) | 4.7 | (2.6–6.8) |
| 2 domains | ||||||||
| card/musc | 20.8 | (11.0–30.6) | 28.1 | (16.2–40.0) | 9.5 | (1.7–17.4) | 11.3 | (2.9–19.6) |
| card/sens | 21.0 | (13.0–29.0) | 13.9 | (6.6–21.2) | 13.3 | (6.4–20.3) | 8.7 | (2.6–14.7) |
| card/respiratory | 19.7 | (12.7–26.6) | 16.9 | (10.8–23.0) | 8.8 | (3.8–13.7) | ||
| card/neurological | 17.6 | (10.8–24.3) | 14.9 | (9.1–20.7) | 12.7 | (7.4–17.9) | 7.2 | (3.2–11.3) |
| musc/sens | 17.0 | (6.6–27.4) | 19.0 | (6.4–31.6) | 11.6 | (3.1–20.2) | 15.0 | (5.7–24.3) |
| musc/respiratory | 15.7 | (6.1–25.3) | 21.9 | (10.0–33.8) | 10.0 | (1.8–18.1) | ||
| musc/neurological | 13.6 | (3.9–23.3) | 20.0 | (8.1–32.0) | 10.9 | (3.4–18.5) | 13.7 | (5.2–22.1) |
| sens/respiratory | 15.9 | (8.8–23.0) | 7.0 | (0.5–13.5) | 10.8 | (4.7–17.0) | 7.3 | (1.9–12.8) |
| sens/neurological | 19.8 | (10.8–28.8) | 27.4 | (16.9–37.8) | 21.3 | (11.5–31.2) | ||
| respiratory/neurological | 17.9 | (11.4–24.5) | 11.7 | (6.0–17.3) | 19.8 | (12.6–27.0) | 12.2 | (6.8–17.5) |
| 3 domains | ||||||||
| card/musc/sens | 38.0 | (26.4–49.6) | 38.0 | (24.5. 51.6) | 31.3 | (17.6–45.0) | 31.9 | (17.7–46.1) |
| card/musc/respiratory | 36.3 | (25.1–47.4) | 40.7 | (27.9–53.8) | 24.2 | (10.9–37.0) | 24.0 | (10.0–38.0) |
| card/musc/neurological | 34.3 | (22.7–45.9) | 38.9 | (25.8–51.9) | 30.1 | (17.3–42.9) | 29.8 | (16.3–43.2) |
| card/sens/respiratory | 36.6 | (27.2–45.9) | 24.9 | (15.8–34.0) | 30.0 | (19.1–40.8) | 19.5 | (8.8–30.2) |
| card/sens/neurological | 34.3 | (24.8–43.7) | 22.6 | (13.3–31.9) | 35.7 | (25.0–46.3) | 25.5 | (15.1–36.0) |
| card/respiratory/neurological | 32.4 | (23.9–40.8) | 26.0 | (18.3–33.7) | 29.0 | (20.0–38.1) | 16.9 | (9.0–24.9) |
| musc/sens/respiratory | 32.5 | (20.2–44.8) | 31.2 | (16.7–45.8) | 27.4 | (13.8–41.1) | 30.0 | (15.6–44.4) |
| musc/sens/neurological | 30.1 | (17.3–42.9) | 29.0 | (14.0–44.1) | 33.4 | (20.1–46.6) | 35.3 | (21.5–49.0) |
| musc/respiratory/neurological | 28.4 | (16.4–40.4) | 32.3 | (18.5–46.2) | 26.5 | (13.9–39.0) | 27.7 | (14.3–41.1) |
| sens/respiratory/neurological | 28.4 | (19.3–37.4) | 14.3 | (5.2–23.4) | 32.1 | (21.9–42.4) | 23.4 | (13.5–33.2) |
a All analyses adjusted for sex, level of education, marital status and living situation.
b Models also adjusted for other disease domains