Table 2. Accuracy of risk stratification scores for sepsis, 95% CI within brackets.
| RETTS RED | RETTS <RED | NEWS2 ≥5 | NEWS2 <5 | SEWS ≥7 | SEWS <7 | SHEWS ≥10 | SHEWS <10 | |
|---|---|---|---|---|---|---|---|---|
| Cohort A | ||||||||
| With sepsis | 66 | 167 | 152 | 81 | * | * | * | * |
| Without sepsis | 12 | 261 | 55 | 219 | * | * | * | * |
| Sensitivity | 28 (23–35) | 65 (59–71) | * | * | * | * | ||
| Specificity | 95 (92–98) | 80 (75–85) | * | * | * | * | ||
| AUC | 0.74 (0.70–0.79) | 0.80 (0.76–0.84) | * | * | * | * | ||
| p (NEWS2) | 0.05 | reference | ||||||
| 30-day mortality | 4 | 10 | 10 | 4 | 12 | 2 | 11 | 3 |
| 30-day survival | 74 | 418 | 197 | 295 | 146 | 346 | 257 | 235 |
| OR 30-day mort | 2.3 (0.7–7.4) | 3.7 (1.2–12.1) | 14.2 (3.1–64.3) | 3.4 (0.9–12.2) | ||||
| Cohort B | ||||||||
| With sepsis | 74 | 55 | 108 | 21 | 108 | 21 | 107 | 22 |
| Without sepsis | 149 | 157 | 198 | 108 | 212 | 94 | 162 | 144 |
| Sensitivity | 57 (48–66) | 84 (76–90) | 84 (76–90) | 83 (75–89) | ||||
| Specificity | 51 (46–57) | 35 (30–41) | 31 (26–36) | 47 (41–53) | ||||
| AUC | 0.55 (0.49–0.60) | 0.69 (0.63–0.74) | 0.67 (0.61–0.73) | 0.73 (0.68–0.79) | ||||
| p (NEWS2) | <0.01 | reference | 0.63 | 0.32 | ||||
| 30-day mortality | 20 | 8 | 26 | 2 | 26 | 2 | 27 | 1 |
| 30-day survival | 158 | 166 | 221 | 103 | 240 | 84 | 186 | 138 |
| OR 30-day mort | 2.6 (1.1–6.1) | 6.1 (1.4–26.0) | 4.5 (1.1–19.6) | 20.0 (2.7–149.2) | ||||
* Not able to validate, derived in this cohort