Table 1. Pearson correlation coefficients (r) of mRNA expression levels of PCOS-candidate genes in human fetal ovaries and their gestational ages (n = 15).
| Age | FBN3 | GATA4 | HMGA2 | TOX3 | LHCGR | DENND1A.V1-7 | DENND1A.V1,3,4 | |
|---|---|---|---|---|---|---|---|---|
| FBN3 | -0.906b | |||||||
| GATA4 | -0.593a | 0.767c | ||||||
| HMGA2 | -0.685b | 0.852d | 0.934d | |||||
| TOX3 | -0.033 | -0.134 | -0.078 | -0.115 | ||||
| LHCGR | -0.491 | 0.421 | 0.020 | 0.287 | 0.081 | |||
| DENND1A.V1-7 | -0.595a | 0.697b | 0.782c | 0.864d | 0.302 | 0.291 | ||
| DENND1A.V1,3,4 | -0.674b | 0.790c | 0.808c | 0.904d | 0.232 | 0.357 | 0.982d | |
| FSHR | -0.545a | 0.575a | 0.680b | 0.606a | -0.185 | -0.033 | 0.445 | 0.421 |
a P < 0.05
b P < 0.01
c P < 0.001
d P < 0.0001; Pearson correlation tests.