Table 2. Pearson correlation coefficients (r) of mRNA expression levels of PCOS-candidate genes and gestational age in bovine fetal ovaries (n = 27).
Age | FBN3 | GATA4 | HMGA2 | TOX3 | LHCGR | FSHB | DENND1A. X1,2,3,4 | C8H9orf3 | RAB5B | ERBB4 | YAP1 | SUOX | RAD50 | THADA | KRR1 | INSR | FSHR | AMH | AR | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FBN3 | -0.887d | |||||||||||||||||||
GATA4 | -0.709d | 0.898d | ||||||||||||||||||
HMGA2 | -0.898d | 0.959d | 0.849d | |||||||||||||||||
TOX3 | -0.892d | 0.824d | 0.670d | 0.826d | ||||||||||||||||
LHCGR | 0.332 | -0.156 | -0.079 | -0.177 | -0.382a | |||||||||||||||
FSHB (PPEx3)* | -0.563b | 0.406a | 0.182 | 0.443a | 0.678c | -0.403a | \ | |||||||||||||
DENND1A.X1,2,3,4 | -0.606c | 0.696d | 0.777d | 0.675c | 0.731d | -0.311 | 0.347 | |||||||||||||
C8H9orf3 | -0.393a | 0.543b | 0.671c | 0.506b | 0.511b | -0.256 | 0.295 | 0.841d | ||||||||||||
RAB5B | -0.314 | 0.246 | 0.340 | 0.258 | 0.485a | -0.459a | 0.471a | 0.714d | 0.644c | |||||||||||
ERBB4 | 0.305 | -0.240 | -0.161 | -0.256 | -0.164 | 0.162 | 0.049 | 0.010 | 0.044 | 0.278 | ||||||||||
YAP1 | -0.080 | 0.236 | 0.491b | 0.217 | 0.225 | -0.387a | 0.064 | 0.637c | 0.716d | 0.692d | 0.232 | |||||||||
SUOX | 0.175 | 0.140 | 0.403a | 0.083 | -0.037 | 0.073 | -0.250 | 0.505b | 0.639c | 0.392a | 0.073 | 0.722d | ||||||||
RAD50 | -0.497b | 0.405a | 0.359 | 0.434a | 0.600c | -0.577b | 0.563b | 0.526b | 0.430a | 0.690d | 0.186 | 0.490b | 0.054 | |||||||
THADA | 0.380 | -0.264 | 0.001 | -0.231 | -0.268 | 0.177 | -0.176 | 0.217 | 0.435a | 0.359 | 0.225 | 0.557b | 0.585b | 0.059 | ||||||
KRR1 | -0.352 | 0.379 | 0.368 | 0.463a | 0.515b | -0.478a | 0.505b | 0.663c | 0.586b | 0.600c | -0.110 | 0.589b | 0.430a | 0.591b | 0.334 | |||||
INSR | 0.775d | -0.601c | -0.312 | -0.643c | -0.632c | 0.248 | -0.435a | -0.143 | 0.167 | 0.116 | 0.369 | 0.392a | 0.572b | -0.283 | 0.756d | -0.070 | ||||
FSHR | 0.753d | -0.580b | -0.436a | -0.640c | -0.684d | 0.675c | -0.531b | -0.392a | -0.203 | -0.196 | 0.451a | -0.062 | 0.256 | -0.391a | 0.456a | -0.432a | 0.729d | |||
AMH | 0.682d | -0.525b | -0.408a | -0.542b | -0.632c | 0.846d | -0.427a | -0.476a | -0.310 | -0.374 | 0.242 | -0.306 | 0.153 | -0.619c | 0.313 | -0.438a | 0.573b | 0.818d | ||
AR | 0.765d | -0.669c | -0.420a | -0.654c | -0.648c | 0.234 | -0.452a | -0.258 | -0.028 | -0.047 | 0.055 | 0.137 | 0.420a | -0.358 | 0.491b | -0.040 | 0.696d | 0.476a | 0.568b | |
TGFB1I1 | 0.853d | -0.664c | -0.413a | -0.695d | -0.676c | 0.231 | -0.444a | -0.188 | 0.034 | 0.024 | 0.432a | 0.292 | 0.518b | -0.352 | 0.584b | -0.032 | 0.876d | 0.669c | 0.537b | 0.772d |
a P < 0.05
b P < 0.01
c P < 0.001
d P < 0.0001; Pearson correlation tests.
*Primer pair from exon 3.