Table 3. MICs of pretomanid and delamanid against different mycobacterial strains.

	Pretomanid		Delamanid
Strain	Reduction (nmol min-1 μmolenzyme-1)	MIC (μg mL-1)	Reduction (nmol min-1 μmolenzyme-1)	MIC (μg mL-1)
M. tuberculosis H37Rva	366 ± 33c	4	103 ± 7.59 c	32
M. tuberculosis N0008a,b	N/D	256	12.1 ± 2.72 c	32
M. marinum M	230 ± 14.4 c	16	326 ± 7.11 c	16
M. smegmatis mc2155	N/D	>50*	N/D	>50*

N/D–Below limit of detection

^aMIC was determined by reazurin assay, measuring the minimal cell death concentration

^bS78Y mutation

^cData used previously in Table 2, and Figs 4 and 6

*MICs obtained from Upton, A. et al. [33]