Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
X-ray crystal structure of the closed complex between yeast TIM (yTIM) and DHAP (PDB ID: 1NEY(45)), which shows the positions of the following active-site side chains relative to the substrate DHAP: K12, E97, E165, P166, I170, and L230. In this study, we have examined single and/or double amino acid substitutions at each of these positions.
