Comparison 3. Prostacyclin analogues.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Iloprost vs. Placebo (IV infusions only)	2		Peto Odds Ratio (Peto, Fixed, 95% CI)	Subtotals only
1.1 patient global assessment of improvement (# improved)	0	0	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.0 [0.0, 0.0]
1.2 number of digital ulcers healed	1	11	Peto Odds Ratio (Peto, Fixed, 95% CI)	23.17 [2.20, 243.52]
1.3 side effects	2	166	Peto Odds Ratio (Peto, Fixed, 95% CI)	9.44 [5.05, 17.67]
1.4 physician global assessment (# improved)	1	122	Peto Odds Ratio (Peto, Fixed, 95% CI)	2.61 [1.27, 5.38]