Table 2:
TEG Changes Following Inhibition of the C3a and C5a receptor.
| Control Median (IQR) |
C3aR Inhibitor Median (IQR) |
C5aR Inhibitor Median (IQR) |
P value | |
|---|---|---|---|---|
| Reaction time (minutes) | 11.2 (9.2 – 11.5) | 11.6 (10.5 – 12.7) | 11.4 (9.0 – 13.7) | 0.36 |
| Angle (degrees) | 42.3 (36.6 – 49.6) | 45.5 (39.9 – 51.9) | 45.7 (40.6 – 51.5) | 0.18 |
| MA (mm) | 52.0 (48.1 – 59.0) | 52.3 (50.1 – 55.6) | 54.3 (50.0 – 58.0) | 0.43 |
| LY30 (%) | 1.6 (1.2 – 3.9) | 4.0 (0.9 – 9.2) | 5.0 (1.5 – 7.7) | 0.19 |
R – reaction time, MA – Maximal Amplitude, LY30 – Lysis 30 minutes after MA, IQR – interquartile range. C3aR – C3a receptor, C5aR – C5a receptor.