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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: J Immunol. 2020 Jan 17;204(5):1274–1286. doi: 10.4049/jimmunol.1901127

Figure.1. LTBI/Ss coinfection is associated with decreased monocyte activation and increased M2 polarization.

Figure.1.

Baseline and antigen-stimulated frequencies of monocytes expressing activation and M2 markers were determined by flow cytometry in Ss+ (light grey n =15) and Ss− (dark grey n =15) individuals. The (A) baseline (unstimulated) as well as (B) PPD, (C) WCL and (D) P/I stimulated frequencies of monocytes expressing activation markers (CD54, CD80, CD86) and M2 markers (CD163 and CD206) are shown. Each circle represents a single individual and the bars represent the GM values. Net frequencies were calculated by subtracting baseline frequencies from the antigen-induced frequencies for each individual. The p values were calculated using the Mann–Whitney U test.