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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: J Immunol. 2020 Jan 17;204(5):1274–1286. doi: 10.4049/jimmunol.1901127

Figure.2. LTBI/Ss coinfection is associated with diminished monocyte phagocytosis and respiratory burst activity.

Figure.2.

Baseline and antigen stimulated frequencies of monocytes were assessed for phagocytic activity and respiratory burst activity in Ss+ (light grey n =10) and Ss− (dark grey n =10) individuals. (A) PBMC were stimulated with WCL, LPS and P/I for 6 h and the frequencies of monocytes undergoing phagocytosis was measured. (B) PBMC were stimulated with WCL, LPS and P/I and the frequencies of monocytes undergoing respiratory burst was measured. Each circle represents a single individual and the bars represent the GM values. Net frequencies were calculated by subtracting baseline frequencies from the antigen-induced frequencies for each individual. The p values were calculated using the Mann–Whitney U test.