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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: J Immunol. 2020 Jan 17;204(5):1274–1286. doi: 10.4049/jimmunol.1901127

Figure.6. Anthelmintic therapy reverses the diminished phagocytosis or respiratory burst activity in monocytes in LTBI/Ss coinfection.

Figure.6.

Baseline and antigen stimulated frequencies of monocytes were assessed for phagocytic activity and respiratory burst activity by flow cytometry in Ss+ (light grey n =10) individuals before and after treatment with a standard dose of ivermectin and albendazole (A) PBMC were stimulated at baseline (unstimulated), WCL, LPS and P/I for 6 h and the frequencies of monocytes undergoing phagocytosis was measured. (B) PBMC were stimulated at baseline (unstimulated), WCL, LPS and P/I for 6 h and the frequencies of monocytes undergoing respiratory burst activity was measured. Each line represents a single individual. Net frequencies were calculated by subtracting baseline frequencies from the antigen-induced frequencies for each individual. The p values were calculated using the Wilcoxon signed rank test.