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Observed signal decay in benign and malignant lesions depending on baseline T2 signal. Tissues and lesions with a very low water content (e.g., fibrotic parenchyma, scars, low cellular cancers with extensive desmoplastic stromal fibrosis) may not be visible on high b value images and present with an artefactual low signal decay leading to low ADC values. S0 indicates signal intensity at b = 0 s/mm2
