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. 2020 Feb 20;11:972. doi: 10.1038/s41467-020-14780-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Representative TGGE showing the T_m of 3WJ-10 PTXs (M = 20 nucleotides monomer) and 4WJ-X-24 PTXs (M = 40 nucleotides monomer) nanoparticles. b Quantitative calculation of T_m from the representative TGGE for 3WJ-10 PTXs and 4WJ-X-24 PTXs nanoparticles. c T_a comparison of 4WJ-X-24 PTXs (orange) and 3WJ-10 PTXs (green) nanoparticles in a representative annealing curve, measured by RT-PCR (n = 3 independent samples over three independent measurements). d Enzymatic stability curve of 4WJ-X nanoparticles after incubation in 50% FBS at 37 °C over time points. Source data are provided as a Source Data file.