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. 2020 Feb 20;10:3009. doi: 10.1038/s41598-020-59514-1

Figure 3.

Figure 3

Top causal network explaining observed gene expression differences. Master regulator TXN is at the hub of the network, controlling upstream regulators of observed gene expression difference, including EGFR. Solid line: direct interaction; broken line: indirect interaction. Orange: Predicted activation; Blue: predicted inhibition. Causal network analysis was conducted using Ingenuity Pathway Analysis tools.