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. 2020 Feb 20;40(2):BSR20193629. doi: 10.1042/BSR20193629

Figure 4. Chronic low-dose LPS does not enhance P301L-mediated microglia activation and GC attenuates hTau-induced activation of microglia in both CA3 and DG subsets.

Figure 4

Mice were treated as described in Figure 2. (A) Activation of microglia (IBA1) was measured by immunohistochemical staining. Hippocampus (Hp) scale bar, 200 μm; CA3 and DG scale bar, 100 μm. (B) Average optical density (AOD) was used to analyze the activation of microglia. Data were present as mean ± SD (n = 3 each group, two-way ANOVA followed by Tukey post hoc test). *, P < 0.05; **, P < 0.01 versus Vector-PBS. ##, P < 0.01 versus P301L-LPS-GC.