Table 2. Highly significant SNPs identified in Cmax group following regression analysis (P<0.0001).
| Name | Chr | Gene | Location | g1 | n1 | m1 | s1 | g2 | n2 | m2 | s2 | P VALUE |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| rs11165069 | 1 | ABCA4 | intron | CC | 22 | 175.40 | 95.28 | TC | 1 | 831.52 | 0.000001 | |
| rs7637682 | 3 | SLC9A10 | intron | AA | 22 | 175.40 | 95.28 | AG | 1 | 831.52 | 0.000001 | |
| rs4234409 | 3 | SLC9A10 | intron | AA | 22 | 175.40 | 95.28 | AC | 1 | 831.52 | 0.000001 | |
| rs4434123 | 3 | SLC9A10 | missense | AA | 22 | 175.40 | 95.28 | AG | 1 | 831.52 | 0.000001 | |
| rs17446282 | 3 | SLC9A10 | intron | AA | 22 | 175.40 | 95.28 | AG | 1 | 831.52 | 0.000001 | |
| rs2291550 | 12 | ABCC9 | synonymous | CC | 22 | 175.40 | 95.28 | TC | 1 | 831.52 | 0.000001 | |
| rs1051640 | 17 | ABCC3 | synonymous | AA | 22 | 175.40 | 95.28 | AG | 1 | 831.52 | 0.000001 | |
| rs757220 | 19 | SLC25A42 | intron | CC | 22 | 175.40 | 95.28 | TC | 1 | 831.52 | 0.000001 | |
| rs12150890 | 19 | SLC7A9 | synonymous | AA | 22 | 175.40 | 95.28 | AG | 1 | 831.52 | 0.000001 | |
| rs17724104 | 20 | SLC9A8 | intron | AA | 22 | 175.40 | 95.28 | AG | 1 | 831.52 | 0.000001 | |
| rs6781844 | 3 | SLC9A10 | missense | TG | 1 | 831.52 | TT | 22 | 175.40 | 95.28 | 0.000001 | |
| rs9855755 | 3 | SLC9A10 | intron | AG | 1 | 831.52 | GG | 22 | 175.40 | 95.28 | 0.000001 | |
| rs4646196 | 5 | SLC22A4 | intron | AG | 1 | 831.52 | GG | 22 | 175.40 | 95.28 | 0.000001 | |
| rs17847036 | 10 | CYP2C9 | synonymous | AG | 1 | 831.52 | GG | 22 | 175.40 | 95.28 | 0.000001 | |
| rs7248399 | 19 | SLC25A42 | intron | AG | 1 | 831.52 | GG | 22 | 175.40 | 95.28 | 0.000001 | |
| rs10417974 | 19 | SLC25A42 | 3UTR | TC | 1 | 831.52 | TT | 22 | 175.40 | 95.28 | 0.000001 | |
| rs215096 | 16 | ABCC1 | intron | TC | 3 | 527.07 | 264.40 | TT | 20 | 155.45 | 73.41 | 0.000015 |
Abbreviations: Chr, chromosome; N, number; g1, genotype 1; n1, number 1; s1, standard deviation 1; g2, genotype 2; n2, number 2; s2, standard deviation 2. *Table only shows several significant SNPs from a total of 1498 highly significant SNPs.