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. 2020 Feb 14;10:36. doi: 10.3389/fonc.2020.00036

Figure 1.

Figure 1

Integrin α3 is overexpressed in cervical cancer tissue and cell lines. (A) The results of the quantitative real-time (qRT)-PCR analysis showed the mRNA levels of ITGA3 expression in different cervical cancer cell lines. Normal cervix (NC) tissue was used as the normal control. (B) Western blotting was applied to show the protein levels of integrin α3 in different cervical cancer lines. (C) Quantification results of the protein intensity of (B). (D) Results of the qRT-PCR analysis of ITGA3 expression in normal cervix tissue (n = 12) and cervical cancer (CC) tissue (n = 39). (E) Western blotting was used to analyze the protein expression of integrin α3 in NC (n = 4) and CC (n = 7). (F) Quantification results of the protein intensity of (E). (G) Immunohistochemistry (IHC) assays were performed to investigate the protein expression of integrin α3 in three trial pairs of NC and CC. Original magnification: ×100. *P < 0.05 vs. corresponding control; **P < 0.01; ***P < 0.001.