Table 1.
Correlation between integrin α3 expression and clinicopathological characteristics of patients with cervical cancer.
| Clinicopathological variable | Integrin α3 | P-value | ||
|---|---|---|---|---|
| Total (n = 142) | Low expression | High expression | ||
| AGE, YEARS | ||||
| ≤42 | 55 | 33 | 22 | |
| >42 | 87 | 42 | 45 | 0.174 |
| FIGO STAGE | ||||
| Ia2 | 8 | 3 | 5 | |
| Ib1 | 99 | 55 | 44 | |
| Ib2 | 10 | 4 | 6 | |
| IIa1 | 16 | 6 | 10 | |
| IIa2 | 9 | 7 | 2 | 0.960 |
| TUMOR SIZE | ||||
| ≤4 | 114 | 62 | 52 | |
| >4 | 28 | 13 | 15 | 0.451 |
| PATHOLOGIC TYPE | ||||
| Squamous cell carcinoma | 113 | 58 | 55 | |
| Adenocarcinoma | 20 | 12 | 8 | |
| Adenosquamous carcinoma | 9 | 5 | 4 | 0.501 |
| STROMAL INVASION | ||||
| <1/2 | 55 | 26 | 29 | |
| ≥1/2 | 87 | 49 | 38 | 0.294 |
| LYMPHOVASCULAR SPACE INVASION | ||||
| Yes | 16 | 10 | 6 | |
| No | 126 | 65 | 61 | 0.412 |
| DIFFERENTIATION GRADE | ||||
| Well | 11 | 3 | 8 | |
| Moderate | 51 | 23 | 28 | |
| Poor | 80 | 49 | 31 | 0.014* |
| PELVIC LYMPH NODE METASTASIS | ||||
| Yes | 29 | 18 | 11 | |
| No | 113 | 57 | 56 | 0.265 |
| VAGINAL INVOLVEMENT | ||||
| Yes | 3 | 3 | 0 | |
| No | 139 | 72 | 67 | 0.099 |
| PARAMETRIAL INFILTRATION | ||||
| Yes | 2 | 2 | 0 | |
| No | 140 | 73 | 67 | 0.180 |
| RECURRENCE | ||||
| Yes | 13 | 2 | 11 | |
| No | 129 | 73 | 56 | 0.005** |
| VITAL STATUS AT FOLLOW-UP | ||||
| Alive | 123 | 72 | 51 | |
| Expired | 19 | 3 | 16 | 0.002** |
FIGO, International Federation of Gynecology and Obstetrics.
*
P < 0.05.
**
P < 0.01.
Bold values represent p < 0.05.