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. 2020 Feb 14;10:36. doi: 10.3389/fonc.2020.00036

Table 2.

Univariate and multivariate analyses of factors associated with overall survival and disease-free survival.

Clinicopathological variable Overall survival Disease-free survival
Univariate Multivariate Univariate Multivariate
Total (n = 142) P-value RR (95% CI) P-value P-value RR (95% CI) P-value
AGE, YEARS
≤42 55
>42 87 0.399 N N 0.393 N N
FIGO STAGE
Ia2 8
Ib1 99
Ib2 10
IIa1 16
IIa2 9 0.630 N N 0.631 N N
TUMOR SIZE
≤4 114
>4 28 0.262 N N 0.268 N N
PATHOLOGIC TYPES
Squamous cell carcinoma 113
Adenocarcinoma 20
Adenosquamous carcinoma 9 0.332 N N 0.336 N N
STROMAL INVASION
<1/2 55
≥1/2 87 0.443 N N 0.437 N N
LYMPHOVASCULAR SPACE INVASION
Yes 16
No 126 <0.001* 0.905 (0.215–3.811) 0.892 <0.001* 1.179 (0.297–4.686) 0.815
DIFFERENTIATION GRADE
Well 11
Moderate 51
Poor 80 0.414 N N 0.409 N N
PELVIC LYMPH NODE METASTASIS
Yes 29
No 113 <0.001* 0.240 (0.069–0836) 0.025* <0.001* 0.234 (0.069–0.794) 0.020*
VAGINAL INVOLVEMENT
Yes 3
No 139 0.530 N N 0.529 N N
PARAMETRIAL INFILTRATION
Yes 2
No 140 0.610 N N 0.609 N N
RECURRENCE
Yes 13
No 129 <0.001* 0.009 (0.002–0.043) <0.001* <0.001* 0.007 (0.001–0.037) <0.001*
INTEGRIN α3 EXPRESSION
Low 75
High 67 0.002* 0.173 (0.042–0.721) 0.016* 0.002* 0.184 (0.044–0.760) 0.019*

RR, relative risk; CI, confidence interval; N, not applicable; FIGO, International Federation of Gynecology and Obstetrics.

*

P < 0.05.

Bold values represent p < 0.05.