Table 2.
Clinicopathological variable | Overall survival | Disease-free survival | |||||
---|---|---|---|---|---|---|---|
Univariate | Multivariate | Univariate | Multivariate | ||||
Total (n = 142) | P-value | RR (95% CI) | P-value | P-value | RR (95% CI) | P-value | |
AGE, YEARS | |||||||
≤42 | 55 | ||||||
>42 | 87 | 0.399 | N | N | 0.393 | N | N |
FIGO STAGE | |||||||
Ia2 | 8 | ||||||
Ib1 | 99 | ||||||
Ib2 | 10 | ||||||
IIa1 | 16 | ||||||
IIa2 | 9 | 0.630 | N | N | 0.631 | N | N |
TUMOR SIZE | |||||||
≤4 | 114 | ||||||
>4 | 28 | 0.262 | N | N | 0.268 | N | N |
PATHOLOGIC TYPES | |||||||
Squamous cell carcinoma | 113 | ||||||
Adenocarcinoma | 20 | ||||||
Adenosquamous carcinoma | 9 | 0.332 | N | N | 0.336 | N | N |
STROMAL INVASION | |||||||
<1/2 | 55 | ||||||
≥1/2 | 87 | 0.443 | N | N | 0.437 | N | N |
LYMPHOVASCULAR SPACE INVASION | |||||||
Yes | 16 | ||||||
No | 126 | <0.001* | 0.905 (0.215–3.811) | 0.892 | <0.001* | 1.179 (0.297–4.686) | 0.815 |
DIFFERENTIATION GRADE | |||||||
Well | 11 | ||||||
Moderate | 51 | ||||||
Poor | 80 | 0.414 | N | N | 0.409 | N | N |
PELVIC LYMPH NODE METASTASIS | |||||||
Yes | 29 | ||||||
No | 113 | <0.001* | 0.240 (0.069–0836) | 0.025* | <0.001* | 0.234 (0.069–0.794) | 0.020* |
VAGINAL INVOLVEMENT | |||||||
Yes | 3 | ||||||
No | 139 | 0.530 | N | N | 0.529 | N | N |
PARAMETRIAL INFILTRATION | |||||||
Yes | 2 | ||||||
No | 140 | 0.610 | N | N | 0.609 | N | N |
RECURRENCE | |||||||
Yes | 13 | ||||||
No | 129 | <0.001* | 0.009 (0.002–0.043) | <0.001* | <0.001* | 0.007 (0.001–0.037) | <0.001* |
INTEGRIN α3 EXPRESSION | |||||||
Low | 75 | ||||||
High | 67 | 0.002* | 0.173 (0.042–0.721) | 0.016* | 0.002* | 0.184 (0.044–0.760) | 0.019* |
RR, relative risk; CI, confidence interval; N, not applicable; FIGO, International Federation of Gynecology and Obstetrics.
P < 0.05.
Bold values represent p < 0.05.