Table 2. Cumulative 24 h urine volume, sodium, chloride and creatinine excretions in patients with ESRD after furosemide monotherapy and coadministration of furosemide and hydrochlorothiazide (Means ± S.D.).
| Parameters of 24 h Urine | Monotherapy (baseline) | Coadministration (baseline) |
|---|---|---|
| Volume (ml) | 2094 ± 810* (1643 ± 529) | 2164 ± 701* (1595 ± 509) |
| Sodium (mEq) | 149.4 ± 59.5* (89.6 ± 28.2) | 151.7 ± 60.8* (75.8 ± 39.9) |
| Chloride (mEq) | 154.6 ± 66.5* (87.2 ± 41.1) | 142.8 ± 61.2* (64.6 ± 35.3) |
| Creatinine (mg) | 850.7 ± 288.5 (910.5 ± 311.8) | 821.3 ± 258.9 (856.7 ± 233.5) |
*: p < 0.05 when compared with baseline (E0). None of the parameters showed difference between monotherapy and coadministration.