Table 4.
Factors of dementia subgroup and sensitivity analysis by using time-dependent Cox regression analysis.
| Anticholinergic medications (With vs. Without) | Time-dependent Cox regression | ||||
|---|---|---|---|---|---|
| Sensitivity analysis | Dementia subgroup | aHR | 95% CI | 95% CI | P |
| Overall | All dementia | 1.043 | 0.958 | 1.212 | 0.139 |
| AD | 1.115 | 0.990 | 1.296 | 0.060 | |
| VaD | 1.039 | 0.975 | 1.208 | 0.149 | |
| Other degenerative dementia | 1.031 | 0.964 | 1.207 | 0.178 | |
| First 2 years excluded | All dementia | 1.040 | 0.977 | 1.208 | 0.089 |
| AD | 1.112 | 0.987 | 1.290 | 0.075 | |
| VaD | 1.023 | 0.961 | 1.188 | 0.224 | |
| Other degenerative dementia | 1.036 | 0.973 | 1.205 | 0.138 | |
| First 4 years excluded | All dementia | 1.024 | 0.962 | 1.190 | 0.162 |
| AD | 1.087 | 0.982 | 1.263 | 0.077 | |
| VaD | 0.994 | 0.934 | 1.155 | 0.394 | |
| Other degenerative dementia | 1.023 | 0.961 | 1.189 | 0.248 | |
PYs, Person-years; aHR, Adjusted hazard ratio: Adjusted for the variables listed in Table 1 .; CI, confidence interval; AD, Alzheimer dementia; VaD, Vascular dementia; P, Chi-square test on category variables and t-test on the continuous variables.