Skip to main content
. 2020 Feb 3;34:136–145. doi: 10.1016/j.molmet.2020.01.011

Figure 2.

Figure 2

MBOAT7 expression increases with ccRCC severity and correlates with poorer survival. (A) MBOAT7 mRNA expression in ccRCC patients with increasing severity of histological grade in patient tumor biopsies. NAT = normal adjacent tissue. (B) A validation dataset from the cancer genome atlas (TCGA) stratified by pathological staging (I-IV) and pan-cancer normalized. (C) High MBOAT7 expression significantly correlated with a decrease in overall survival in TCGA patients stratified by Grade 3 and Grade 4 histological neoplasms. Similarly, high MBOAT7 expression correlated with a decrease in overall survival with Stage III and IV patients. One-way ANOVA and log-rank test (Mantel–Cox test) ns > 0.1234, *<0.05, **<0.002, and ***<0.0002.