Table 1.
Collections of human biological material in Biobank@VITO.
| Study | Collection period | Population | Number participants | Gender (%) (male/female) | Sample types | Biobank samples N | Storage |
|---|---|---|---|---|---|---|---|
| FLEHS I | 2002–2004 | Newborns | 1,196 | 52/48 | Cord blood Cord blood plasma Cord bloodDNA |
1,799 1,974 117 |
−20°C −20°C −80°C |
| 2003–2004 | Adolescents (14–15 y) | 1,679 | 53.1/46.9 | Peripheral blood Serum Urine |
1,636 1,445 1,688 |
−20°C −20°C −20°C |
|
| 2004–2005 | Adults (50–65 y) | 1,583 | 49/51 | Peripheral blood Serum Urine |
1,526 1,489 1,581 |
−20°C −20°C −20°C |
|
| FLEHS I birth cohort follow-up | 2013–2014 | Children (10 y) | 133 | 33.1/66.9 | Blood white blood cells Red blood cells Plasma Blood DNA Blood RNA Saliva DNA |
99 300 86 134 100 132 |
−80°C −80°C −80°C −80°C −20°C −80°C |
| FLEHS II | 2008–2009 | Newborns | 255 | 52/48 | Cord blood plasma Cord blood cells Cord blood DNA |
219 254 726 |
−80°C −80°C −80°C |
| 2008–2009 | Adolescentsss (14–15 y) |
210 | 57.6/42.4 | Peripheral blood Serum Urine |
196 64 1,828 |
−80°C −80°C −80°C/−20°C |
|
| 2008–2009 | Adults (20–40 y) | 204 | 47.1/52.9 | Peripheral blood Serum Urine |
406 622 2,033 |
−80°C −80°C −80°C/−20°C |
|
| FLEHS III | 2014 | Newborns | 281 | 53.1/48.8 | Cord blood Cord blood plasma Cord blood cells Hair mother Nails mother |
1,710 122 279 196 159 |
−80°C/−20°C −80°C/−20°C −80°C RT RT |
| 2012–2013 | Adolescentss (14–15 y) |
208 | 45.7/54.3 | Peripheral blood Peripheral blood cells Blood RNA Serum Plasma Urine EBC* |
618 276 92 181 202 496 41 |
−80°C −80°C −20°C −80°C −80°C −80°C −80°C |
|
| 2014 | Adults (50–65 y) | 209 | 46/54 | Peripheral blood Blood DNA Serum Urine |
616 204 333 657 |
−80°C −20°C −80°C −80°C/−20°C |
|
| FLEHS IV + FLEHS I birth cohort (14–15 year) | 2017–2018 | Adolescents (14–15 y) | 611 | 47.2/52.8 | Peripheral blood Peripheral blood cells Blood RNA Serum Urine Hair |
1,306 609 608 1,879 3,009 609 |
−80°C −80°C −20°C −80°C −80°C/−20°C RT |
| 3XG | 2011–2015 | Mother–newborn cohort | 301 | 50.8/19.2 | Cord blood Cord blood cells Cord blood plasma Peripheral blood Serum Urine Breastmilk |
1,039 1,110 930 1,211 721 5,575 196 |
−80°C/−20°C −80°C −80°C/−20°C −80°C −80°C/−20°C −80°C/−20°C −80°C/−20°C |
| DEMOCOPHES | 2011–2012 | Mother (≤45 y)—child cohort (6–11 y) | 129 | 51.2/48.8 | Urine Hair |
873 263 |
−80°C RT |
| Hotspot study: Genk | 2010 | Adolescents (14–15 y) | 197 | 45.2/54.8 | Serum Plasma Urine Red blood cells |
169 552 1,942 137 |
−80°C/−20°C −20°C −80°C/−20°C −20°C |
| Hotspot study: Menen | 2011 | Adolescents (14–15 y) | 199 | 57.3/42.7 | Serum Plasma Urine Red blood cells |
177 585 2331 195 |
−80°C/−20°C −20°C −80°C/−20°C |
| Hotspot study: Ghent canal zone | 2013 | Adolescents (14–15 y) | 200 | 50.5/49.5 | Peripheral blood Peripheral blood cells Serum Plasma Urine EBC* |
789 249 180 94 564 752 |
−80°C/−20°C −80°C −80°C −80°C −80°C −80°C |
*
EBC, exhaled breath condensate.