TABLE 2.
List of protein-loaded liposomes in clinical use.
| Commercial name | Active protein | Treatment | Company | Status | Year | References |
| Epaxal | Hepatitis A virus proteins | Hepatitis-A | Crucell (former Berna Biotech Ltd.) | On market | 1994 | Cryz, 1999 |
| Inflexal-V | Influenza virus proteins | Trivalent influenza vaccine | Crucell (former Berna Biotech Ltd.) | On market | 1997 | Herzog et al., 2009 |
| Curosurf | SP-B and SP-C proteins | Lung activator for stress disorder | Chiesi Farmaceutici | On market | 1999 | Walther et al., 2000 |
| T4N5 liposome lotion | T4 endonuclease V (T4N5) enzyme | Skin cancer | AGI Dermatics Inc. | Phase III | 2007 | Bulbake et al., 2017 |
| Hepatic-directed vesicles-insulin (HDV-I) | Insulin | Diabetes | Diasome Pharmaceuticals | Phase II | 2019 | Diasome_Pharmaceuticals, 2019 |
| Biphasix | INF-α | Genital warts and cervical dysplasia | Altum Pharmaceuticals | Phase I/II | 2011 | Altum_Pharmaceuticals_Inc, 2019 |
| IL-2 liposomes | IL-2 | Pulmonary metastases | Biomira United States | Phase I | 2000 | Skubitz and Anderson, 2000 |