PACTR201411000928146.

Trial name or title	IMSI versus ICSI in patients with severe male factor infertility and repeated ICSI failure
Methods	Randomised controlled trial, performed in an academic setting (Egypt)
Participants	Elegibility criteria: primary or secondary infertility, aged 18 to 37 years old, having good ovarian reserve (AMH > 1.5, AFC > 5, and basal FSH < 10 mIu/L), and at least one previously failed ICSI Male partner with severe oligospermia (sperm concentration < 5 x 106/mL) and severe teratospermia (normal form < 4%)
Interventions	Couples were randomised in two groups: Intervention: sperm selection performed at 10,000x magnification with a Nomarski‐contrast Nikson inverted microscope Control: sperm selection under regular (200x) magnification
Outcomes	Number of embryos, fertilisation rate, embryo grading, implantation rate, and pregnancy rate.
Starting date	January 2014
Contact information	Prof. Mohmoud Al Abd: dr.mohmoudalabd@gmail.com
Notes	According to PACTR Registry, study is open to recruitment. Authors were contacted for further information, but we did not receive a response by the time of completion of the present update.