Table 3. Baseline characteristics and outcomes associated with an emergent ribotype 255 compared to two other endemic ribotypes in Houston, Texas.
Ribotype | |||||
---|---|---|---|---|---|
255 n = 50 |
027 n = 50 |
p-value 255 vs 027 |
014–020 n = 50 |
p-value 255 vs 014–020 |
|
Age, mean years (±SD) | 59.3 (±16.8) | 69.3 (±13.6) | 0.001 | 61 (±18.3) | 0.63 |
CCI score, median (IQR) | 2 (1–3) | 3 (2–5) | 0.014 | 2 (1–4) | 0.34 |
Initial clinical cure, no. (%) | 38 (76) | 30 (60) | 0.09 | 38 (76) | Not tested |
Severe/fulminant disease, no. (%) | 19 (38) | 40 (80) | <0.001 | 20 (40) | 0.83 |
CDI complications† | 5 (10) | 14 (28) | 0.02 | 9 (18) | 0.25 |
30d recurrence, no. (%) | 2 (4) | 2 (4) | Not tested | 3 (6) | 0.64 |
90d recurrence‡, no. (%) | 5 (10) | 10 (20) | 0.17 | 4 (8) | 0.70 |
All-cause 30d mortality, no (%) | 5 (6) | 8 (16) | 0.37 | 6 (12) | 0.75 |
Abbreviations: Charlson Comorbidity Index (CCI), standard deviation (SD), C. difficile infection (CDI).
†Includes ICU admission, colectomy, ileus, and toxic megacolon, ‡90-day recurrence includes those with 30-day recurrence.