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. 2020 Jan 10;9(2):e014582. doi: 10.1161/JAHA.119.014582

Table 4.

In‐Hospital All‐Cause Death, and Length and Cost of Hospitalization by Year

2012 (N=4915) 2013 (N=9813) 2014 (N=12 009) 2015 (N=11 984) 2016 (N=12 626) 2017 (N=3022) P Values
PE patients/DVT patients 1384/3531 4821/4992 6321/5688 6404//5580 7073/5553 1884/1138 <0.001a
In‐hospital all‐cause death 213 (4.3%) 527 (5.4%) 781 (6.5%) 722 (6.0%) 757 (6.0%) 200 (6.6%) <0.001a
 In‐hospital all‐cause death  in PE patients 143/1384 (10.3%) 443/4821 (9.2%) 665/6321 (10.5%) 606/6404 (9.5%) 650/7073 (9.2%) 172/1884 (9.1%) 0.15a
 In‐hospital all‐cause death  in DVT patients 70/3531 (2.0%) 84/4992 (1.7%) 116/5688 (2.0%) 116/5580 (2.1%) 107/5553 (1.9%) 28/1138 (2.5%) 0.33a
Length of hospital stay, d 16 (9‐25) 16 (10‐24) 15 (9‐23) 14 (8‐22) 14 (8‐21) 13 (8‐19) <0.001b
 Length of hospital stay  in PE patients, d 20 (13‐31) 17 (11‐26) 16 (10‐24) 15 (9‐23) 15 (9‐22) 13 (8‐20) <0.001b
 Length of hospital stay  in DVT patients, d 14 (9‐23) 14 (9‐21) 14 (8‐21) 13 (8‐20) 12 (7‐20) 12 (7‐18) <0.001b
Cost of hospitalization (Japanese yen) 709 821 (407 223‐1 265 617) 724 879 (432 995‐1 223 130) 705 839 (428 489‐1 142 785) 678 703 (410 659‐1 115 117) 653 318 (400 483‐1 074 754) 639 843 (398 974‐1 014 805) <0.001b
 Cost of hospitalization in  PE patients (Japanese yen) 1 271 128 (856 237‐1 953 864) 947 670 (578 064‐1 477 492) 861 313 (547 431‐1 324 174) 822 105 (515 383‐1 267 296) 764 853 (481 503‐1 190 960) 715 340 (458 336‐1 079 578) <0.001b
 Cost of hospitalization in DVT  patients (Japanese yen) 550 804 (366 367‐953 045) 559 040 (363 521‐942 797) 540 365 (362 608‐922 006) 536 711 (349 154‐899 444) 525 192 (342 920‐886 537) 524 662 (342 574‐881 519) <0.001b
Cost of hospitalization (US dollarsc) 6453 (3702‐11 506) 6590 (3936‐11 120) 6417 (3896‐10 389) 6170 (3734‐10 137) 5939 (3641‐9771) 5817 (3628‐9226) <0.001b
 Cost of hospitalization in PE  patients (US dollarsc) 11 556 (7784‐17 763) 8615 (5255‐13 432) 7830 (4977‐12 038) 7474 (4686‐11 521) 6954 (4378‐10 827) 6503 (4166‐9814) <0.001b
 Cost of hospitalization in DVT  patients (US dollarsc) 5008 (3331‐8664) 5082 (3305‐8571) 4913 (3296‐8382) 4879 (3174‐8177) 4774 (3117‐8059) 4770 (3115‐8014) <0.001b

Continuous variables are presented as the median and interquartile range. DVT indicates deep vein thrombosis; JROAD‐DPC, Japanese Registry of All Cardiac and Vascular Diseases—Diagnosis Procedure Combination; PE, pulmonary embolism.

a

Changes of categorical variables were evaluated using the Cochran‐Armitage test for trend.

b

Changes of continuous variables were evaluated using Jonckheere‐Terpstra test for trend. The current analysis in the JROAD‐DPC database included between April 2012 and March 2017, and 2012 and 2017 were partial years.

c

1 dollar=110 Japanese yen.