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. 2020 Jan 18;9(2):e013784. doi: 10.1161/JAHA.119.013784

Figure 4.

Figure 4

Transglutaminase cross‐linked gelatin significantly increased retention of implanted adipose‐derived mesenchymal stem cells post MI. A, Representative images of CM‐DiI labeled adipose‐derived mesenchymal stem cells (ADSCs) in hearts 3, 7, 14, 28, and 42 days after myocardial infarction (MI). Heart tissue was immunostained for CM‐DiI (red), troponin T (green), and DAPI (blue). B, Quantification of ADSCs in the peri‐infarct area was performed by calculating the percentage of the red‐colored area in the infarcted area (Trop T negative area) (n=20 from 4 mice). CM‐DiI indicates Chloromethylbenzamido 1,1′‐dioctadecyl‐3,3,3′,3′‐tetramethylindocarbocyanine perchlorate; Col‐Tgel, Transglutaminase cross‐linked Gelatin. Data were analyzed by unpaired Student t‐test. **P<0.01.